NAD+ Therapy in Edmonton

Dr. Muradov offers Edmonton NAD+ Therapy.

The most experienced NAD+ practitioner in Edmonton

Administered thousands of NAD+ treatments since 2015

Energy & brain fog often improve with NAD+ Therapy.

We offer Edmonton NAD, Glutathione and Vitamin C Therapy.

Offering NAD+ to Edmonton since 2015

NAD Therapy in Edmonton

NAD+ Background 

Nicotinamide adenine dinucleotide (NAD+) is present in all cells of the body and is crucial for cell viability and function.

NAD+ is a cofactor essential for operation of the Krebs Cycle and Electron Transport Chain for body wide ATP production. 

The phosphorylated metabolite of NAD+, NADP+ with its redox couple NADPH drives a number of reactions, including cholesterol and nucleic acid synthesis, and regeneration of glutathione. 

NAD+ activates Sirtuin pathways of which, Sirtuin1 (SIRT1) is the pathway associated with longevity as well as the PARP enzyme family that controls DNA repair. 

The clinical importance of maintaining cellular NAD+ levels was established initially with the finding that pellagra, which is characterized by diarrhea, dermatitis, dementia and death, could be cured with foods containing the NAD+ precursor niacin (Vitamin B3).

Our Naturopaths tend to give Niacinamide during NAD therapy - Niacinamide and Niacin are chemically inter-convertable. 

Cellular concentrations of NAD⁺ have been shown to decrease under conditions of increased oxidative damage such as aging which is partly why NAD+ is given as a longevity promoting substance.

Interventions targeted at restoring NAD+ levels have been shown in animal models to support healthy aging and improve metabolic function and cognitive function. 

Our clinic usually doses NAD+ anywhere from 100-2000mg.

However, doses between 250-500mg are most often given for fatigue whereas doses beyond 1000mg are typically for substance withdrawal.

NAD+ Uses

Our Naturopaths tend to suggest NAD+ Therapy in a few common scenarios: Fatigue, Longevity, Substance Withdrawal.

We also consider NAD+ for issues where mitochondrial function is thought to be affected like Fibromyalgia. 

NAD+ as a treatment is relatively new however robust data exists for NADH (reduced version)

One such study "Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome" where NADH (10mg) in Chronic Fatigue Syndrome improved Fatigue, Cognition, muscle aches and weakness and sleep.

In our experience, the use of NAD+ Therapy provides much more robust results that NADH

Our Naturopaths may recommend NADH as a bridging treatment between NAD treatments.

We also have experience giving NADH for neurodegenerative disease and instances where we suspect mitochondrial defects.

In general, we've seen more profound responses with NAD+ than NADH.

NADH is given more rapidly than NAD+ and does not have anywhere near the same side effects as NAD+. 

Fairly robust data exists for the use of NADH in Parkinson's in particular - see Birkmayer 1993.

Other studies exist evaluating NADH and CoQ10 for Chronic Fatigue Syndrome with positive results as well.

So CoQ10 is often an oral consideration our Naturopaths suggest in conjunction with NAD+ Therapy. 

However our Naturopaths have a preference for using NR in conjunction with NAD+ as NR has been shown to effectively increase NAD+ levels in the blood.

NAD+ Administration 

Our Naturopaths often suggest front loading the NAD+ with a few consecutive days of administration at the outset.

However, once weekly treatments are efficacious as well, with patients needing a booster ever 2-4 weeks in many cases.

NAD+ can give profound nausea when the treatment is given too rapidly.

NAD+ is rapidly and completely removed from the plasma (taken up by cells) for the first two hours administration.

Enzymes indicative of hepatic stress such as the intrahepatic LD and AST and the post-hepatic (bile duct) enzyme GGT all decline immediately following NAD+ Therapy suggesting that the integrity of these tissues is in fact enhanced following NAD Therapy. 

We've found that the older a client is, the larger magnitude of effect we see from NAD+ treatment, as tissue levels of NAD+ naturally decline with age.

NAD+ treatments can be enhanced with the inclusion of a Vitamin Cocktail.

The B-Vitamins and Magnesium in particular can help drive the Krebs cycle and enhance effects seen especially with regards to fatigue.

The B-Vitamins and NAD+ can be co-administered in one treatment for simultaneous synergistic effect. 

Glutathione can easily be added to the tail end of NAD+ Therapy for enhanced longevity enhancing effects as Glutathione is thought to protect mitochondrial DNA. 

NAD+ and Withdrawal

NAD+ was originally used for alcoholism and it appears to be less effective for tobacco and marijuana.

For marijuana and tobacco, NAC (N-acetyl cysteine) is one of our top Naturopathic recommendations typically. Our Naturopathic Doctors often use Vitamin C, B1 and B3 in addition to NAD+ for alcohol cessation. 

For substance abuse, NAD+ Therapy can be anywhere from 3 - 10 consecutive days.

Alcohol, Cocaine and Crystal meth are thought to be the best candidates for NAD+ Therapy.

Benzodiazepines (lorazepam, clonazepam, diazepam) are thought to be the hardest (may require up to 15 days). 

Within a handful of NAD+ treatments often reported calmness, clarity of thought as well as a reduction in cravings and improved energy are seen.

NAD+ Therapy in Edmonton 

Need NAD+ Therapy?

 (780) 757-8378