Vitamin IV Therapy Drips at TruMed Naturopath Clinic
We offer Edmonton a full range of Intravenous Vitamin Drips
Dr. Muradov has been offering Edmonton a large array of IV Therapy Drips & Infusions since 2010.
Energy, Mood, Focus, Immunity, Cosmetics and Cancer are the most common reasons for IV therapy treatment
Many of our IV Drips are enhanced by Hyperbaric Oxygen Treatment which is exclusively offered at TruMed.
IV Therapy Clinic in Edmonton
It's easy to try any of our IV Drips
Please call 780 757 8378 and you can book in just for IV therapy.
One of our Naturopaths will help choose the ideal IV treatment for you.
Many of our IV Therapy drips synergize with Hyperbaric Oxygen Treatment.
Try IV therapy for these conditions:
The typical Western diet provides only marginal amounts of a wide range of vitamins and minerals. At our Edmonton office, patients frequently remark that they have more energy when they take an oral multivitamin preparation.
Our basic nutritional IV therapy gives B1, B2, B3, B5, B6, B12 and Magnesium (The Myers') - all of which are directly involved in the energy production cycle (Krebs cycle) other than B6.
For patients that do not experience substantial benefit from IV Vitamin drips, we frequently consider the use of IV NAD+. NAD+ has gained much notoriety as a Sirtuin activator (Sirtuins are NAD+ dependent enzymes that remove acyl groups in histones) and regulate a large range of cellular processes including longevity. PARP enzymes also use NAD+ and are involved in DNA repair.
NAD Drips are tolerated well by most however, in women in particular, they can cause fairly intense chest pressure and nausea if given too quickly. 250mg per hour is a common infusion rate and doses for fatigue are usually between 250-500mg per treatment. IV NAD treatments are also built up once weekly for 3-4 weeks and then are given every 2-4 weeks as a "booster."
In terms of mitochondrial supports, our office also offers intramuscular injections of PolyMVA. PolyMVA is an analogue of Lipoic Acid and it's a cofactor for pyruvate dehydrogenase for conversion of pyruvate to acetyl-CoA, which bridges glycolysis with the citric acid cycle. PolyMVA has been studied in Lyme & MS related fatigue.
B12 shots are often considered in fatigue as well, in particular because B12 is inexpensive, frequently effective and is quickly administered either in office or at home. B12 is used to make Succinyl-CoA - which is also part of the Krebs cycle and when converted to succinate, it's involved in the electron transport chain for even more ATP production.
Bottom Line: Our Naturopathic Doctors have a range of IV Therapy treatments for fatigue - Vitamin Drips & NAD+ are out hardest hitters for stubborn fatigue.
Mood - A number of different nutritional, hormonal, and herbal treatments have been found to be effective in the treatment of depression. In our experience, in many cases, an appropriately chosen naturopathic treatment program produces results that are as good as, or better than, those achieved with conventional drug therapy, while causing fewer adverse side effects. At our Edmonton office, we frequently interweave herbal, nutritional and IV therapy options for both anxiety and depression.
Many different nutrients play a role in regulating mood, and a deficiency of one or more of these nutrients could contribute to depression. For example, the amino acids tryptophan and tyrosine and a number of micronutrients are required for the synthesis of serotonin and norepinephrine respectively.
At our office our Naturopaths frequently use 5-HTP (Tryptophan metabolite and immediate precursor to serotonin). In clinical trials, 5-HTP was at least as effective as, and somewhat better tolerated than, fluvoxamine and fluoxetine (both SSRIs). 5-HTP & tryptophan are available for use in IV therapy treatments.
Depression is one of the reversible manifestations of vitamin B12 and folate deficiency so our Naturopaths frequently try shots of B12 & folate before transitioning to IV Therapy drips where the quantity of these can be greatly increased. Vitamins B1, B3, B6 and Vitamin C have also been implicated in low mood. In terms of minerals, zinc, and magnesium can also contribute to low mood as well so we frequently screen for deficiency of these, of which, both can be easily repleted in IV format. Our IV therapy drips for mood contain B1, B2, B3, B5, B6, B12, Magnesium, Zinc and Vitamin C.
Immunity - In term of immunity, consumption of allergenic foods might increase susceptibility to infection by suppressing immune function or by promoting inflammation and congestion of mucous membranes. Our Naturopathic doctors have found that many patients with a history of recurrent infections experience fewer infections after they identify hidden food allergens. Therefore, our Naturopaths frequently run food sensitivity testing in patients with poor immunity and recurrent infections.
Vitamin C is a nutrient we can dose heavily in IV format. IV doses of vitamin C produce markedly higher serum concentrations of the vitamin than those obtainable by oral administration of maximum tolerated doses.
Vitamin C has a direct antiviral and antibacterial effect and has been shown to kill a wide range of viruses and bacteria in vitro and has been found to stimulate the production of interferon (an endogenous antiviral compound).
Zinc and Selenium play roles in host defenses against infections and suboptimal zinc status appears to be common among people consuming a typical Western diet. Zinc and Selenium supplementation has been shown to decrease the incidence of infections such as pneumonia. Our Naturopathic doctors always add Zinc and Selenium to IV Therapy treatments for fatigue.
Vitamin A plays a role in immune function and has been shown to inactivate a number of different viruses in vitro. Vitamin A also enhances the capacity of epithelial tissue to resist invasion from infectious agents. Vitamin A cannot be given intravenously so our Naturopaths frequently suggest oral supplementation or dietary sources of Vitamin A.
Dilute hydrogen peroxide IV drips are also used at our office principally in the treatment of chronic infections as well.
Skin Health - We can administer IV Glutathione and IV Vitamin C to our Edmonton patients looking for skin lightening and brightening effects with our Glutathione IV.
Glutathione is formed from three amino acids glutamine, cysteine, and glycine. Very frequently our Naturopathic doctors use cysteine as a way of increasing Glutathione orally. Glutathione is produced in the transsulfuration pathway from homocysteine.
Glutathione has been reported to play an important role in inducing skin lightening through inhibiting melanogenesis.
The stimulation of lighter pheomelanin pigment synthesis by Glutathione is also thought to be one main cosmetic mechanisms of action.
In a 2019 study, hyperpigmentation was induced in the skin of experimental animals and then glutathione was injected three times a week for three consecutive weeks. Glutathione at 40 mg/kg reduced skin hyperpigmentation (reduced melanin granules) significantly and there were no issues with liver or kidney function from this treatment.
The authors concluded IV Glutathione "was effective as a skin lightening agent."
In a 2021 study, topical and oral glutathione were given to adults for 8 weeks and the combination group showed significantly lower melanin index relative to placebo. The authors concluded "this study showed that topical and oral glutathione were effective skin-lightening agents."
In a 2012 study, orally administered glutathione at 500 mg per day for 4 weeks did result in some modest lightening in human subjects: "at 4 weeks, the melanin indices decreased consistently at all six sites in subjects who received glutathione."
IV Glutathione is extremely well tolerated and our Naturopathic doctors frequently use it as an add on to other IV Therapy drips. In recent years however, the most common request is to use Glutathione drips for cosmetic purposes as discussed above.
Thiamine - Vitamin B1
Riboflavin - Vitamin B2
Niacinamide - Vitamin B3
Dexpanthenol - Vitamin B5
Pyridoxine - Vitamin B6
Cobalamin - Vitamin B12
Ascorbate - Vitamin C
Folic Acid - 5-MTHF or B9
Alpha Lipoic Acid & PolyMVA
Select IV Ingredients In-Depth
B1 (Thiamine) - B1 is absolutely central to energy production as it's needed in the first step of energy production to make acetyl-CoA from pyruvate. Carbohydrates, fats and proteins are first converted to acetyl-CoA, most often via pyruvate.
Our Naturopathic Doctors usually add 150-200 mg of B1 to our IV Therapy infusions for energy.
B2 (Riboflavin) - B2 is the precursor to FAD (the coenzyme form of B2) and the Krebs cycle uses this to create FADH2 which is a key electron donor in the electron transport chain to create ATP. This intimate role with energy production is why our Naturopaths consider riboflavin for treatment of migraines.
Our naturopaths add additional B2 to all of our IV drips for energy which gives them an extreme orange color.
B3 (Niacin/Niacinamide) - We use Niacinamide in our Intravenous treatments, which is a precursor to NAD+ (via the salvage pathway) which in the Citric Acid Cycle, at multiple points, to create NADH for use as an electron donor in the electron transport chain.
This is precisely why NAD+ IV Therapy can be so helpful for energy production. Our office is a leader for IV NAD+ in Edmonton.
B5 (Pantothenic Acid) - Pantothenic acid acts as a precursor to coenzyme A (CoA) which is used in the generation of Acetyl-CoA for entry into the Krebs cycle.
B6 (Pyridoxine) - Our office uses two forms of B6 in our IV Therapy treatments - pyridoxine hydrochloride as well as the bioactive form pyridoxal 5′-phosphate.
B6 is involved in the functioning of over 140 separate enzymes in the body and is therefore a crucial part of our body biochemistry.
B12 (Cobalamins) - Our Naturopathic doctors use two forms of B12 mainly in our IV treatments: Adenosylcobalamin (mitochondria) as well as Methylcobalamin (cytosol) which are co-factors for Methylmalonyl-CoA Mutase and Methionine Synthase respectively (see graphic).
Methylmalonyl-CoA is converted to Succinyl-CoA which is part of the Krebs cycle and when it's converted to succinate, it's involved in the electron transport chain for ATP production
B12 is certainly a favorite at our Edmonton office for rapidly improving energy in mood in both shot and intravenous drip format.
Vitamin C (Ascorbic Acid) - Vitamin C is of course an important water soluble antioxidant and can regenerate other antioxidants within the body and plays an important role in immune function.
Intestinal absorption of vitamin C is regulated specific dose-dependent, active transport. Exceeding a certain dose orally and additional Vitamin C ends up in the large bowel. For this reason, Intravenous Vitamin C administration is a superior method for obtaining large doses of Vitamin C in the blood.
Clinically, we've observed the upper threshold for most adults is about 5 grams of Vitamin C orally before causing diarrhea. Intravenously, our Naturopathic Doctors frequently give doses between 5 and 75 grams with no digestive side effects whatsoever.
Folate - The previously described reaction of Homocysteine converted to methionine (via methionine synthase & methylcobalamin) uses the methylated form of Folate (MTHF) to create SAMe which is involved in the creation of both Dopamine and Serotonin.
Clinical studies have shown that adding Folate to conventional antidepressants seems to improve treatment response in patients with major depressive disorder so our Naturopathic doctors frequently add MTHF to our IV therapy drips for mood.
Magnesium - Magnesium is one of the most important ingredients in our IV drips. Magnesium, like Vitamin C, does reach a maximum dose orally before giving digestive side effects so intravenous administration is a superior way to improve blood levels.
Magnesium as with other vitamins, exerts pharmacologic actions when given intravenously such as promoting relaxation of both vascular and and bronchial smooth muscle. The relaxation effects are thought to be a major contributor to how our Vitamin IV therapy can help in conditions such as asthma, migraine, anxiety and insomnia.
Magnesium is central to mitochondrial energy production so it's an important component of Vitamin IVs for fatigue as Magnesium is actually complexed to ATP. Our Naturopathic doctors frequently consider the use of Magnesium Aspartate in fatigue for this reason.
Intravenously our office uses both Magnesium Sulfate and Magnesium Chloride because both are readily available in the Edmonton area. We are easily able to give doses around 1000mg of either preparation which easily exceeds a daily oral dose of Magnesium which is usually in the order of 400-600mg.
IV Therapy & Cancer
Most frequently our Naturopathic Doctors use IV Vitamin C and IV Alpha Lipoic Acid in the context of Alternative Cancer Care for our Edmonton patients.
IV Vitamin C: Intravenous administration achieves a high concentration of Vitamin C in the blood, it's distributed to the extracellular fluid and identical concentrations are achieved both in the plasma and in extracellular fluid.
In the extracellular fluid Vitamin C is oxidized and releases an electron (and becomes the ascorbate radical) and the electron it gives out is transferred to an O2 molecule to make superoxide. Through superoxide dismutation (two hydrogens combine with superoxide) hydrogen peroxide is produced.
This process of hydrogen peroxide production does not occur when Vitamin C is given orally. Vitamin C must be given intravenously to achieve sufficient concentrations for this process to occur. Intravenous Vitamin C doses for Cancer frequently range between 15 to 85 grams with 50-75 grams as the most common IV therapy doses.
Many case reports exists demonstrating that IV Vitamin C has a role in Alternative Cancer Care. Breast Cancer, Lymphoma, Pancreatic, Liver, Ovarian, Kidney and Bladder cancer are some of the cancers with published benefits. For a complete discussion please visit EICT.ca.
Furthermore, data exists suggesting safe co-administration of IV Vitamin C therapy with many chemotherapies.
In particular a review from Bazzan looked at 54 patients who received ascorbic acid in conjunction with chemotherapy. For all patients receiving intravenous Vitamin C, there was a significant improvement or stability in fatigue, bowel habits, and pain symptoms.
We estimate that our Naturopathic Doctors have administered about 3000 IV Vitamin C treatments at our Edmonton office. The overall incidence of side effects is extremely low, likely below 1%. Dehydration, and fatigue are the most commonly seen issues with high dose Vitamin C.
Limiting factors with respect to IV Vitamin C are typically time and cost. Costs for a standard Intravenous Vitamin C treatment in Edmonton is typically $160-$185. Administration times are usually 100 minutes to 150 minutes, not including set up time.
Alpha Lipoic Acid - Alpha Lipoic Acid is the preferred metabolic cancer treatment our Naturopaths use at our Edmonton office. It is a free radical scavenger made naturally in the body and it inhibits NF-κB activation and regenerates Vitamin C, E and Glutathione.
In terms of it's role in metabolic cancer care, Lipoic Acid is cofactor for the pyruvate dehydrogenase which converts pyruvate into acetyl CoA for the Krebs cycle. Lipoic acid also inhibits pyruvate dehydrogenase kinase which inhibits pyruvate dehydrogenase. Because of these actions, it is an inhibitor of aerobic glycolysis, a common mechanism for energy production in cancer cells and is thought to be a synergist with Hyperbaric Oxygen therapy.
Numerous case reports exist supporting the role of Lipoic acid in cancer care, usually where it's combined with Hydroxycitric acid and Low Dose Naltrexone "LDN." LDN is available in the Edmonton area, our Naturopathic Doctors can refer you for an LDN prescription to one of our allied health providers if it's indicated in your case.
Case reports using IV Alpha Lipoic Acid by Berkson (for Kidney and Pancreatic Cancer) as well as by Schwartz (for numerous Cancers including Colon, Uterine and Brain) demonstrate preliminary efficacy.
Lipoic Acid infusions in the Edmonton area range between $165-$185 but infusion times are short - usually around 30 minutes. Lipoic acid intravenous drips are well tolerated unless given too rapidly - dizziness and headaches are possible because of blood sugar lowering effects of the infusion.
Our Naturopaths have administered thousands of Intravenous drips at our Edmonton office.
Please contact us for your complimentary IV consultation.